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The Leukemia/Bone Marrow Transplant Program of BC

Hematology Dictionary
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A type of white blood cell derived from the thymus (hence T cells) involved in controlling immune reactions. Uncontrolled proliferation of this type of cell gives rise to T cell lymphoma/lymphoma.

Testicular Relapse
Recurrence of leukemia in the testicles. The disease may be restricted to the testicles or may also show evidence of disease in either the bone marrow or CNS. Treatment will depend on the timing and extent of relapsed disease.

See platelet.

An over-production of platelets. See also essential thrombocythemia.

Shortage of platelets leading to problems with bleeding.

The development of a clot in a blood vessel, usually in a vein but sometimes in an artery. Potentially life-threatening if left untreated.

A gland at the base of the neck concerned with the production of functional T-cells.

An x-ray picture of internal organs of the body.

Total Body Irradiation (TBI)
Radiotherapy often given in several doses prior to bone marrow transplantation with the aim of killing any residual leukemia in the patient. It is used in conjunction with high dose anti-cancer drugs. The procedure and its side effects will be discussed individually with the patient.

A term to describe either the change of a normal cell into a cancerous cell, or the acceleration of disease in chronic myeloid leukemia from the chronic to a more acute phase characterized by the production of large numbers of blast cells.

A chromosome abnormality in which the part of one chromosome has become transferred to another. See also Philadelphia chromosome.

Trephine Biopsy
Removal of a small "core" of bone marrow under local anesthetic. It is used to assess bone marrow structure, the number and distribution of all the blood cell types. The trephine biopsy is normally done at the same time as a bone marrow aspirate.

Term which indicates the presence of an additional whole chromosome.

An accumulation of abnormal cells, which may be benign or malignant.


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The information in this glossary is cited with permission from the Leukemia Research Foundation web site.


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