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The Leukemia/Bone Marrow Transplant Program of BC

Chemotherapy Drugs


Cyclophsphamide (sigh-kloe-FOSS-fa-mide) is a drug that is used to treat many types of cancer. It is a clear liquid that is injected into a vein.

Common Side Effects

  • Nasal congestion, runny eyes and nose and sneezing may occur during or immediately after administration of cyclophosphamide.
  • Mouth sores can occur a few days after treatment. These can occur on the tongue, the sides of the mouth or in the throat. Follow good oral hygiene to prevent infection.
  • Hair loss is common. It may begin within 3-6 weeks after start of treatment. Your hair may thin or you may become totally bald. You may lose hair on your face and body. Your hair will grow back once your treatments are over.
  • Bladder inflammation may occur. If your treatment allows, drink plenty of fluids and empty your bladder frequently every 2 hours for at least a day after your dose.
  • Loss of appetite and weight are common. This may persist long after your treatments with cyclophosphamide are over.

Printable Drug Information

Click here, to view and print a complete description of cyclophosphamide and its side effects and management from the BC Cancer Agency Drug Manual©.

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