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The Leukemia/Bone Marrow Transplant Program of BC

Chemotherapy Drugs


Melphalan (MEL-fa-lan) is a drug that is used to treat many types of cancer. It is a clear liquid that is injected into a vein.

Common Side Effects

  • Melphalan burns if it leaks under the skin. Tell your nurse or doctor immediately if you feel burning, stinging or any other change while the drug is being given.
  • Pain or tenderness may occur where the needle was placed.
  • Nausea and vomiting may occur after your treatment. It may last for 48 hours.
  • Mouth sores may occur a few days after treatment. These may occur on the tongue, on the sides of the mouth or in the throat. Follow good oral hygiene to prevent infection.
  • Hair loss sometimes occurs with melphalan. Colour and texture may change. If hair loss does occur, your hair will grow back once you stop the treatment.

Printable Drug Information

Click here, to view and print a complete description of melphalan and its side effects and management from the BC Cancer Agency Drug Manual©.

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